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 Coregistering ROIs to anatomical files
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D.Smith
Starting Member

USA
2 Posts

Posted - Jun 15 2006 :  2:57:58 PM  Show Profile  Reply with Quote
We draw ~16 ROIs onto each subject's anatomical scan. We scan each subject twice. Is there a way to coregister the ROIs from the first scan to the second anatomical file, so that we don't have to draw all 16 ROIs a second time? I realize that their head is not in the exact same position during the second scan- but if we can determine the tilt and movement then shouldn't we also be able to apply that tilt and movement to our previously drawn ROIs?
-Drew

Research Coordinator
UNC School of Medicine
Dept. of Neurology
919.843.1474

petty
BIAC Staff

USA
453 Posts

Posted - Jun 15 2006 :  4:44:27 PM  Show Profile  Reply with Quote
you could coregister the 1st scan to the 2nd scan, then just apply the saved transformation matrix to the ROI file.
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josh.bizzell
BIAC Staff

USA
118 Posts

Posted - Jun 15 2006 :  5:14:37 PM  Show Profile  Reply with Quote
Chris is right. In fact, all you really need is an affine transformation (instead of a higher-order warping) since the brains are from the same subject. Many packages can do this; SPM, AIR, RView, FSL, et al. SPM is probably the easiest to use, and will let you apply the transformation matrix to the ROI image. Make sure to use nearest-neighbor interpolation on the ROI image so the values will remain integers.

- Josh
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