We draw ~16 ROIs onto each subject's anatomical scan. We scan each subject twice. Is there a way to coregister the ROIs from the first scan to the second anatomical file, so that we don't have to draw all 16 ROIs a second time? I realize that their head is not in the exact same position during the second scan- but if we can determine the tilt and movement then shouldn't we also be able to apply that tilt and movement to our previously drawn ROIs? -Drew
Research Coordinator UNC School of Medicine Dept. of Neurology 919.843.1474
Chris is right. In fact, all you really need is an affine transformation (instead of a higher-order warping) since the brains are from the same subject. Many packages can do this; SPM, AIR, RView, FSL, et al. SPM is probably the easiest to use, and will let you apply the transformation matrix to the ROI image. Make sure to use nearest-neighbor interpolation on the ROI image so the values will remain integers.